Hyperinsulinemia and Its Association with Poly Cyctic Ovarian Syndrome
ثبت نشده
چکیده
.. Objective: To determine the variable clinical presentation of Poly cystic ovarian Syndrome (PCOS) & its association with Hyperinsulinaemia in young adolescent girls. Patients & Methods: A descriptive study was conducted for one year from February 2009-2010 at Isra University Hospital Hyderabad (IUH). 136 adolescent girls who came in OPD with suspected features of polycystic ovarian syndrome were recruited. Biochemical test, ultrasound of pelvis and test to determine hyperinsulinemia were done .woman having preexisting ovarian pathology were excluded. All results were analyzed on statistical software SPSS version 16. Frequencies and percentages were calculated. Result: Insulin resistance significantly increased (43.4 %) in girls who have shown the features of PCOS. Weight gain observed in 69 (50.7 % Obese) and 40(29.4%very obese) of girls respectively. Different types of menstrual irregularities such as oligomenorrhea 50(36.8%), secondary amenorrhea 28 (20.6%) primary amenorrhea 5 (3.7%) were observed. 53(39.0%) adolescent girls had normal cycle but evidence of PCO on ultrasound. Infertility was found in 32 (23.5%) of participant followed by hirsutism& acne in 59 (43.4%) 45 (33.1%) of woman respectively. Conclusions: There is significant association of PCOS with hyperinsulinemia. Hyperinsulinemia if persist can lead to metabolic syndrome with its serious sequelae .Steps should be taken for early recognition of PCOS in young woman.
منابع مشابه
I-37: Pathogenesis of PCOS and N AcetyCysteine, A Novel Remedy for Poly Cystic Ovarian Syndrome
Background: Poly cystic ovarian syndrome (PCOS) is the most prevalent endocrinopathy among women and the most common underlying diagnosis for anovulatory infertility. The role of insulin-resistance (IR) and hyperinsulinemia in pathophysiology and clinical manifestations of the syndrome depicts the importance of evaluation of the efficacy of insulin reducing medications. N acetyl cysteine (NAC) ...
متن کاملN Acetyl Cysteine, A novel Remedy for Poly Cystic Ovarian Syndrome
Background Poly cystic ovarian syndrome (PCOS) is the most prevalent endocrinopathy among women and the most common underlying diagnosis for anovulatory infertility. The role of insulin-resistance (IR) and hyperinsulinemia in pathophysiology and clinical manifestations of the syndrome depicts the importance of evaluation of the efficacy of insulin reducing medications. N acetyl cysteine (NAC) i...
متن کاملMale Equivalent Polycystic Ovarian Syndrome: Hormonal, Metabolic and Clinical Aspects
Recent studies identified the presence of a male polycystic ovarian syndrome (PCOS), which mainly affects men whose female relatives are afflicted with PCOS, caused by genes responsible for the susceptibility of this syndrome in women. Similar hormonal, metabolic, and clinical alterations occurring in PCOS women have also been reported in their male relatives, suggesting a association between t...
متن کاملThe survey of abnormal glucose tolerance and insulin resistace and incidence of diabetes type 2 in poly cystic ovary syndrome patients in Shiraz
Background: Polycystic ovarian syndrome is one of the most commen hyper androgenic disorders affecting women, its prevalence being estimated at 5% – 10%. Our goal was to survey abnormal glucose tolerance, insulin resistance and incidence of diabetes type 2 in patients with polycystic ovary syndrome. Materials and methods: This investigation is a descriptive – analytic study which is done to su...
متن کاملAre Lean and Normal Weight Patients with Polycystic Ovarian Syndrome at Risk of Preeclampsia?
Background We examined whether pregnant women with preeclampsia have an increased rate of pre-pregnancy polycystic ovary syndrome (PCOS). This study also evaluated whether the association, if any, was a result of preeclampsia and its relationship to PCOS or dependent upon concurrent obesity. MaterialsAndMethods In this study, 75 preeclampsia cases and 225 normotensive pregnant controls, matched...
متن کامل